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Pharmaceutical & Diagnostic
C-7001

Coelenterazine - native

Coelenterazine is the substrate for the enzymes Renilla luciferase, Gaussia luciferase and other luciferase enzymes. Marine organisms like squids, shrimps, fish and jellyfish use coelenterazine to produce spectacular bioluminescence (in analogy with insects which utilize firefly luciferine). Today, coelenterazine is used in numerous applications like immunoassays, ELISA, and protein based calcium indicators. The isolation and structure determination of coelenterazine was reported independently by two different groups in the seventies who discovered the molecule in sea pansy (Renilla reniformis) and in the cnidarian Aequorea victoria, respectively. Interestingly (PNAS 98 (20): 11148–51) it was also found that the luminescent jellyfish Aequorea victoria does not produce coelenterazine itself but it rather assimilates it through ingestion of small preys like shrimps and copepods.

Products for Pharmaceutical and Diagnostic Industries

The product C-7001 is available on a large scale and is intended for use in the chemical, diagnostic, pharmaceutical and related industries.

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Products for Research and Development

We also offer this substance with CAS No. [55779-48-1] for research and development use under the product code/s:

EC14031 Coelenterazine
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Technical Data

CAS No: 55779-48-1
Synonyms: 2-(p-Hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzyl-imidazo[1,2-a]pyrazin-3-(7H)-one
Product Code: C-7001
MDL No: MFCD00467176
Chemical Formula: C26H21N3O3
Molecular Weight: 423.48

References


Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View
Application Notes: View

CAS No:
55779-48-1
Synonyms:
2-(p-Hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzyl-imidazo[1,2-a]pyrazin-3-(7H)-one
MDL No:
MFCD00467176
Chemical Formula:
Molecular Weight:
423.48
Product Structure
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Click for MSDS

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